What is Cardarine?

Cardarine (Сardarine, Endurobol, GW-501516, Peroximod) is rightfully considered one of the strongest fat burners on the market today. It is a PPARδ receptor agonist, originally developed by Glaxo Smith Kline and Ligand Pharmaceuticals for the treatment of obesity, cardiovascular and metabolic diseases. The action of GW-501516 is entirely aimed at speeding up the process of lipolysis in the body, followed by the conversion of fats into free energy. As a result, you improve your performance, endurance and increase the effectiveness of strength training. Cardarine is recommended for people suffering from metabolic syndrome, in which hormonal disorders occur in the body, gradually leading to the accumulation of fat. It is important to note that Cardarine burns fats without physical exertion.

Effects

  • Powerful fat burning effect,
  • Increase in muscle mass,
  • Improvement of individual strength indicators and the effectiveness of training,
  • Shortening the period of muscle recovery,
  • A noticeable increase in working capacity

Benefits

  • Good compatibility with other drugs,
  • Increases levels of HDL and lowers LDL,
  • Decrease in the number of inflammatory processes in the body,
  • Prevention of cardiovascular diseases and diabetes,
  • Suitable for both men and women,
  • Complete absence of side effects with proper application,
  • IS NOT toxic,
  • Does not require PCT.

Research

Some sources continue to insist on the carcinogenicity of Cardarine, referring to one sensational study in which mice were diagnosed with cancer as a consequence of taking the drug. However, this study, on which most of these sources are based, studied exclusively the effect of super-physiological dosing (10 mg / 1 kg of weight), in other words, a person with a body weight of 90 kg should take 900 mg of the drug per day for a long time, whereas a standard Dosage of GW-501516 is about 20 mg per day. Moreover, in the refutation of previous sources, there are a number of studies, according to which, Cardarine is an anti-inflammatory agent for macrophages, hepatocytes, cardiomyocytes, colon epithelium, keratinocytes, myoblasts, endothelial and immune cells.

One more study should be noted, in which 3 types of colon cells and 2 types of liver cells susceptible to cancer were tested. According to the results obtained using the Coulter method, none of the five samples showed any changes in the cell proliferation, which completely denies carcinogenicity of Cardarine.

Recommendations for the use

The standard dosage of Cardarine is 10-20 mg per day for 12 weeks. At weight over 85 kg it is recommended to increase the daily norm of the drug to 30 mg.

Side effects

When used correctly, Cardarine has no side effects.

Sources:

  1. http://www.ncbi.nlm.nih.gov/pubmed/24767130
  2. http://www.ncbi.nlm.nih.gov/pubmed/25063273
  3. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421799/
  4. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464237/